As a class of drugs, opioids include hydrocodone, oxycodone, fentanyl, heroin and morphine. All opioids are chemically similar, interacting with the nerve cells’ opioid receptors throughout the body and brain. Generally, opioid pain relievers can be safe when taken for an appropriate amount of time with a doctor’s prescription and supervision, but they can lead […]
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The opioid crisis has been a serious problem in Canada for many years. Individuals continue to misuse opioids, leading to a reduced quality of life, accidental overdoses and even death. Everyone wants to see their loved ones who suffer from opioid addiction overcome their struggle, and many of those struggling themselves are seeking recovery. It’s […]
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Injection drug misuse has been an ongoing crisis in Canada for decades. To mitigate some of the risks and provide users with safer alternatives, Needle Exchange Programs (NEPs) have been implemented across the country. NEPs, which are a harm reduction measure, are confidential and free. These programs provide high-risk users with sterile supplies, which helps […]
Continue ReadingMethadone hydrochloride is a synthetic, long-acting µ-opiod receptor agonist, available in Canada for oral use, usually mixed with orange juice. Peak blood levels after oral ingestion occur at 2 to 6 hours. Because of significant protein binding (>90%), levels are constant over 24 hours. In non-tolerant individuals, there is a biexponential decline in serum concentration […]
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